35+ clinical guides — born from a single ABG Mastery Guide on May 22, 2025, and grown into the foundation of ENKI Clinical.
On May 22, 2025, the first guide was published — the ABG Mastery Guide, created in collaboration with Sophia (ChatGPT-4o). That single guide grew into a series of 35+ clinical references spanning anesthesia and critical care.
From October 13 to December 5, 2025, the official Telegram channel ran its daily pearl series — 100 clinical pearls over 53 days, covering 30+ topics. That effort didn't stop — it evolved into ENKI Clinical, a full clinical decision-support platform built to reduce cognitive load in ICU and anesthesia practice.
These guides remain free, always — because the mission began with teaching, and teaching never ends.
Seven specialized ICU & Anesthesia PWAs — born from this series.
Bedside-ready — built for rounds, exams, or independent study in any setting.
The first guide in the series. Step-by-step acid-base logic, compensation rules, delta gap, and ICU-based examples.
Created: 22 May 2025 →Anesthesia machine ventilation — modes, weaning, and extubation for all age groups.
Created: 29 May 2025 →Fluid therapy before, during, and after surgery — including bowel obstruction and special cases.
Created: 02 Jun 2025 →Multimodal analgesia, opioid-sparing strategies, and pain protocols by surgery type and patient profile.
Created: 2025 →Safe, structured care across all age groups — dosing, comorbidities, blocks, and low-resource adaptations.
Created: 2025 →Hemodynamics, risk stratification, anesthesia planning, and postpartum strategy for high-risk maternal care.
Created: 2025 →Frailty scales, safe drug use, anesthesia principles, and recovery strategies for the elderly.
Created: 2025 →Laryngospasm, LAST, embolic crises, and intra-op arrests — structured recognition and response.
Created: 2025 →TTE/TEE views, interpreting echo reports, and making life-saving decisions in the OR & ICU.
Created: 2025 →Spirometry, lung volumes, DLCO, and flow-volume loop analysis for anesthesia and ICU settings.
Created: 2025 →Risk stratification, tailored anesthesia, rescue strategies, and guidance across all resource settings.
Created: 2025 →Single-opioid strategy — pH-safe, crystal-free, optimized for 48-hour pain control in low-resource settings.
Created: 2025 →Intraoperative ECG logic, reflex bradycardia, QTc, antiarrhythmics, and red-flag patterns.
Created: 2025 →Phlegm physiology, airway protection, intraoperative risks, suction protocols, and safe lavage strategies.
Created: 2025 →Safe, balanced transfusion in low-supply hospitals — from FFP cycles to DIC and obstetric hemorrhage.
Created: 2025 →Layer-by-layer guide to safe epidural practice — anatomy, technique, dosing, troubleshooting, and ICU applications.
Created: 2025 →Mixed disorders, oxygenation indices, bicarbonate therapy, and ventilator-linked decisions in the ICU.
Created: 22 May 2025 →Types, clinical signs, hemodynamics, vasopressors, and tailored resuscitation strategies.
Created: 2025 →Recognition, bundle timing, fluid management, vasopressor strategies, and source control.
Created: 2025 →Ventilator modes, settings, waveforms, and real ICU troubleshooting scenarios.
Created: 2025 →Berlin definition, ARDSnet tables, hyaline membranes, prone positioning, and drowning cases.
Created: 2025 →FiO₂ physiology, delivery devices, preoxygenation protocols, and hypoxia correction.
Created: 2025 →Structured bedside checklists, red flags, and medicolegal documentation frameworks.
Created: 2025 →ICU assessment with RASS and CAM-ICU, drug protocols, and sedation strategies.
Created: 2025 →CPAP/ETT management, surfactant administration, emergencies, and NICU challenges.
Created: 2025 →Chronic control, emergency plans, ICU ventilator settings, and weaning pearls.
Created: 2025 →Correction of Na⁺, K⁺, Mg²⁺, Ca²⁺, and PO₄³⁻ with safe, evidence-based protocols.
Created: 2025 →Continuous renal replacement — modes, machine setup, anticoagulation, and alarm management.
Created: 2025 →Bleeding, thrombosis, DIC, HIT, TTP, anticoagulant reversal, and factor replacement.
Created: 2025 →Fluids, insulin, potassium, cerebral edema, and euglycemic DKA — pediatric to limited-resource adaptations.
Created: 2025 →TTM, brain protection, shock support, and survival strategy — ROSC is just the start.
Created: 2025 →Empiric & definitive therapy, MDROs, de-escalation, and stewardship in all resource settings.
Created: 2025 →Anesthesia, ICU care, and red flags from liposuction to bariatric surgery.
Created: 2025 →CPR, ROSC, brain death, and DNAR — structured protocols for every resource level.
Created: 2025 →Stress hyperglycemia, insulin protocols, hypoglycemia rescue, and glucose targets for all ICU settings.
Created: 2025 →Ischemic, hemorrhagic, and subarachnoid stroke — BP modulation, neuro checks, edema control, and thrombolysis protocols.
Created: 01 Jun 2025 →Primary vs. secondary cascade, sedation, hyperosmolar therapy, ICP control, and neuro-monitoring protocols.
Created: 01 Jun 2025 →Timeline-based drug escalation, intubation indications, EEG guidance, and refractory SE management.
Created: 02 Jun 2025 →ICU watch for neuromuscular failure, IVIG/plasma exchange, ventilator weaning, and cardiac monitoring.
Created: 04 Jun 2025 →Trigger recognition, respiratory failure signs, ventilator management, cholinergic vs. myasthenic differentiation.
Created: 05 Jun 2025 →Bacterial meningitis, viral encephalitis, brain abscess — empiric regimens, LP precautions, herniation risk.
Targeted temperature management and neuroprognostication — pupils, EEG, MRI.
Brain tumors with acute decompensation — steroids, seizure control, obstructive hydrocephalus.
GCS, FOUR score, pupillometry, ICP monitoring techniques, CT signs of herniation.
Herniation protocol, seizure algorithm, emergency neuro-rescue in LMIC settings.
Predicting neurologic recovery — scores, SSEP, EEG, and family discussion frameworks.
Non-structural causes of coma — hepatic, septic, uremic, sodium, CO₂.
Clinical confirmation steps, apnea test, pitfalls, and ICU responsibilities.
Conversion disorders, psychogenic seizures, and mimics in the ICU.
Prolonged ventilation, steroid/paralysis-related muscle loss, EMG diagnosis.
100 daily clinical pearls shared from Oct 13 to Dec 5, 2025 — covering 30+ topics in anesthesia and critical care. The channel is now an archive. The journey continued as ENKI Clinical.
To my beloved mother — may God grant her eternal peace.
To my father — whose memory remains a source of strength.
To my brother — deeply missed.
To every patient suffering in silence,
and every clinician striving in hardship,
across all hospitals, all languages, and all limitations.
This series is for you — in need, in service, or in solitude.
نسألكم الدعاء، وقراءة الفاتحة لأرواح أحبتي الراحلين.
— Dr. Amir Fadhel · F.I.C.M.S. A&IC